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Programme

 

Wednesday 23rd October, 2019

 

 Afternoon 17.00 – 19.00

 

 Opening Ceremony

 

Meeting rationale, Giacinto Bagetta, (Cosenza)

 

Welcome address, Gino Mirocle Crisci, Rector of University of Calabria (Cosenza)

 

Welcome address, Maria Luisa Panno, Head of Department of Pharmacy, Health Science and Nutrition, University of Calabria (Cosenza)

Dr Giacomo Giovinazzo, General Manager, Department of Agriculture and Agrifood Resources, Handling Authority for PSR Calabria 2014-2020, Calabria Region

Avv. Ezio Pizzi, President of Unionberg & of Consortium for Protection of  Bergamot, Reggio Calabria

 

 

Opening Lectures

 

17.30-19.00

 

Chairpersons: Shinobu Sakurada (Sendai) / Giacinto Bagetta (Cosenza)

 

Hiroshi Nagase (Tsukuba) Design and synthesis of orexin receptor selective ligands and their pharmacology

 

Cristina Tassorelli (Pavia) at the edge of migraine therapy

 

 

 Welcome Cocktail

 

 

 Thursday 24th October, 2019

 

Morning Session 9.30-13.00

 

 

Basic Mechanisms of Pain

Chairpersons: Diana Amantea (Cosenza) / Makoto Inoue (Urbana-Champaign)

 

9.30 – 10.00 Stefania Ceruti (Milan) Purinergic mechanisms and glial cells  

 

10.00 - 10.30 Oliver J Dolly (Dublin) SNAP-25 cleaving botulinum neurotoxins suppress cytokine-induced elevation of the surface content in drgs of pain transducers, TRP/V1 and /A1 channels

 

10.30 - 11.00 Sabatino Maione (Naples) Role of glutamate and endocannabinoids in the plastic changes associated with neuropathic pain

 

 

Coffee Break

 

 

Basic Mechanisms of Pain

Chairpersons: Luigi A Morrone (Cosenza) / Tsukasa Sakurada (Fukuoka)

 

11.30-12.0 Shiro Kishioka (Wakayama) Peripheral administration of alpha4-beta2 nAChR agonist ameliorates neuropathic pain elicited by type 2 diabetes mellitus in mice.

 

12.00 - 12.30  Kengo Hamamura (Fukuoka) Effects of continuous subcutaneous administration of bergamot essential oil in mice with partial sciatic nerve ligation

 

12.30 – 13.00 Alberto Chiarugi (Florence) Dexpramipexole blocks Nav1.8 sodium channels and affords analgesia in multiple nociceptive and neuropathic pain models

 

 

13.00-15.00 Lunch Break and Poster Discussion

 

 

Afternoon Session 15.00 – 18.30

 

 

Inflammation and Pain

Chairpersons: Laura Berliocchi (Catanzaro) / Kosuke Aritake (Fukuoka)

 

15.00 - 15.30 Hirokazu Mizoguchi (Sendai) Management of morphine-resistant inflammatory pain

 

15.30 – 16.00 Tomonori Kaifu (Sendai) A glycosylation enzyme ameliorates experimental autoimmune encephalomyelitis through increasing ligand for an inhibitory C-type lectin receptor

 

16.00 - 16.30 Makoto Inoue (Urbana-Champaign) Neuroimmunology in inflammatory disease

 

 

Coffee Break

 

 

Histamine in Pain and Itch

Chairpersons: Patrizio Blandina (Florence) / Shinobu Sakurada (Sendai)

 

17.00 – 17.30 Tadaho Nakamura (Sendai) Behavioral changes related to increased brain histamine

 

17.30 – 18.00 Lorenzo di Cesare Mannelli (Florence) Histamine in pain modulation: a role for opioid tolerance management

 

18.00 – 18.30 Mariaconcetta Durante (Florence) Cross-talk between histamine H4 receptor and A3 adenosine receptor on CD4+ T cells in resolution of neuropathic pain states

 

 

Friday 25th October, 2019

 

Morning Session 9.30-13.00

 

Translational Research

Chairpersons: Alberto Chiarugi (Florence) / Hirokazu Mizoguchi (Sendai)

 

9.30 - 10.00 Giulia Magni (Milan) Nutraceuticals and trigeminal pain

 

10.00 - 10.30 Serena Boccella (Naples) Role of PEA in the hippocampal plasticity associated with neuropathic pain

 

10.30 – 11.00 Giovanni Appendino (Novara) Botanicals and Pain

 

 Coffee Break

 

 Translational Research

Chairpersons: Paolo Tonin (Kroton) / Hiroshi Nagase (Tsukuba)

 

11.30 – 12.00 Tatsuro Kohno (Sendai) Underlying mechanisms of acetaminophen in the spinal dorsal horn neurons

 

12.00 – 12.30 Francesca Guida (Naples) Oral cannabidiol prevents chronic pain and neurological dysfunctions in a mouse model of mild traumatic brain injury

 

12.30 – 13.00 Roberto Russo (Naples) TRPM8 modulators in pain perception

 

 

13.00-15.00 Lunch Break and Poster Discussion

 

 

Afternoon Session 15.00 – 18.30

 

Rehabilitation and Pain

Chairpersons: Giorgio Sandrini (Pavia)/ Shiro Kishioka (Wakayama)

 

15.00-15.30 Roberto De Icco (Pavia) Vagus nerve stimulation and pain suppression in migraine

 

15.30 – 16.00 Francesco Riganello (Kroton) Role of autonomic system in the vegetative status

 

16.00 - 16.30 Giorgio Sandrini (Pavia) Italian consensus conference on pain in neurorehabilitation:recommendations in dementia and disorders of consciousness

16.30 - 17.00 Damiana Scuteri (Cosenza) Neuropsychiatric symptoms of dementia: role of pain and essential oil of bergamot as a novel therapeutic

 

 

Coffee Break

 

 

Future Perspectives in Pain Research

Chairpersons: Tatsuro Kohno (Sendai) / Oliver J Dolly (Dublin)

 

17.30 - 18.00 Kosuke Aritake (Fukuoka) Inhibitor for hematopoietic prostaglandin D synthase accelerates wound healing

 

18.00 – 18.30 Ernesto Fedele (Genoa) Modulation of glutamate release by presynaptic NMDA receptors as a functional model to investigate pain mechanisms

 

18.30 Closing Ceremony

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