top of page



Wednesday 23rd October, 2019


 Afternoon 17.00 – 19.00


 Opening Ceremony


Meeting rationale, Giacinto Bagetta, (Cosenza)


Welcome address, Gino Mirocle Crisci, Rector of University of Calabria (Cosenza)


Welcome address, Maria Luisa Panno, Head of Department of Pharmacy, Health Science and Nutrition, University of Calabria (Cosenza)

Dr Giacomo Giovinazzo, General Manager, Department of Agriculture and Agrifood Resources, Handling Authority for PSR Calabria 2014-2020, Calabria Region

Avv. Ezio Pizzi, President of Unionberg & of Consortium for Protection of  Bergamot, Reggio Calabria



Opening Lectures




Chairpersons: Shinobu Sakurada (Sendai) / Giacinto Bagetta (Cosenza)


Hiroshi Nagase (Tsukuba) Design and synthesis of orexin receptor selective ligands and their pharmacology


Cristina Tassorelli (Pavia) at the edge of migraine therapy



 Welcome Cocktail



 Thursday 24th October, 2019


Morning Session 9.30-13.00



Basic Mechanisms of Pain

Chairpersons: Diana Amantea (Cosenza) / Makoto Inoue (Urbana-Champaign)


9.30 – 10.00 Stefania Ceruti (Milan) Purinergic mechanisms and glial cells  


10.00 - 10.30 Oliver J Dolly (Dublin) SNAP-25 cleaving botulinum neurotoxins suppress cytokine-induced elevation of the surface content in drgs of pain transducers, TRP/V1 and /A1 channels


10.30 - 11.00 Sabatino Maione (Naples) Role of glutamate and endocannabinoids in the plastic changes associated with neuropathic pain



Coffee Break



Basic Mechanisms of Pain

Chairpersons: Luigi A Morrone (Cosenza) / Tsukasa Sakurada (Fukuoka)


11.30-12.0 Shiro Kishioka (Wakayama) Peripheral administration of alpha4-beta2 nAChR agonist ameliorates neuropathic pain elicited by type 2 diabetes mellitus in mice.


12.00 - 12.30  Kengo Hamamura (Fukuoka) Effects of continuous subcutaneous administration of bergamot essential oil in mice with partial sciatic nerve ligation


12.30 – 13.00 Alberto Chiarugi (Florence) Dexpramipexole blocks Nav1.8 sodium channels and affords analgesia in multiple nociceptive and neuropathic pain models



13.00-15.00 Lunch Break and Poster Discussion



Afternoon Session 15.00 – 18.30



Inflammation and Pain

Chairpersons: Laura Berliocchi (Catanzaro) / Kosuke Aritake (Fukuoka)


15.00 - 15.30 Hirokazu Mizoguchi (Sendai) Management of morphine-resistant inflammatory pain


15.30 – 16.00 Tomonori Kaifu (Sendai) A glycosylation enzyme ameliorates experimental autoimmune encephalomyelitis through increasing ligand for an inhibitory C-type lectin receptor


16.00 - 16.30 Makoto Inoue (Urbana-Champaign) Neuroimmunology in inflammatory disease



Coffee Break



Histamine in Pain and Itch

Chairpersons: Patrizio Blandina (Florence) / Shinobu Sakurada (Sendai)


17.00 – 17.30 Tadaho Nakamura (Sendai) Behavioral changes related to increased brain histamine


17.30 – 18.00 Lorenzo di Cesare Mannelli (Florence) Histamine in pain modulation: a role for opioid tolerance management


18.00 – 18.30 Mariaconcetta Durante (Florence) Cross-talk between histamine H4 receptor and A3 adenosine receptor on CD4+ T cells in resolution of neuropathic pain states



Friday 25th October, 2019


Morning Session 9.30-13.00


Translational Research

Chairpersons: Alberto Chiarugi (Florence) / Hirokazu Mizoguchi (Sendai)


9.30 - 10.00 Giulia Magni (Milan) Nutraceuticals and trigeminal pain


10.00 - 10.30 Serena Boccella (Naples) Role of PEA in the hippocampal plasticity associated with neuropathic pain


10.30 – 11.00 Giovanni Appendino (Novara) Botanicals and Pain


 Coffee Break


 Translational Research

Chairpersons: Paolo Tonin (Kroton) / Hiroshi Nagase (Tsukuba)


11.30 – 12.00 Tatsuro Kohno (Sendai) Underlying mechanisms of acetaminophen in the spinal dorsal horn neurons


12.00 – 12.30 Francesca Guida (Naples) Oral cannabidiol prevents chronic pain and neurological dysfunctions in a mouse model of mild traumatic brain injury


12.30 – 13.00 Roberto Russo (Naples) TRPM8 modulators in pain perception



13.00-15.00 Lunch Break and Poster Discussion



Afternoon Session 15.00 – 18.30


Rehabilitation and Pain

Chairpersons: Giorgio Sandrini (Pavia)/ Shiro Kishioka (Wakayama)


15.00-15.30 Roberto De Icco (Pavia) Vagus nerve stimulation and pain suppression in migraine


15.30 – 16.00 Francesco Riganello (Kroton) Role of autonomic system in the vegetative status


16.00 - 16.30 Giorgio Sandrini (Pavia) Italian consensus conference on pain in neurorehabilitation:recommendations in dementia and disorders of consciousness

16.30 - 17.00 Damiana Scuteri (Cosenza) Neuropsychiatric symptoms of dementia: role of pain and essential oil of bergamot as a novel therapeutic



Coffee Break



Future Perspectives in Pain Research

Chairpersons: Tatsuro Kohno (Sendai) / Oliver J Dolly (Dublin)


17.30 - 18.00 Kosuke Aritake (Fukuoka) Inhibitor for hematopoietic prostaglandin D synthase accelerates wound healing


18.00 – 18.30 Ernesto Fedele (Genoa) Modulation of glutamate release by presynaptic NMDA receptors as a functional model to investigate pain mechanisms


18.30 Closing Ceremony

bottom of page